Preclinical evidence

The Triflo valve is the result of years of research in collaboration with world leaders in aeronautics, medicine, and science. Exhaustive in-vitro and in-vivo testing performed on the valve suggest its safety and effectiveness.



In-vitro testing

The design of the valve has been validated by means of state-of-the-art experimental and numerical testing:

  • Hydrodynamic performance
  • Structural performance
  • Durability and wear tests



Extensive comparative in-vitro testing has been performed by independent institutes, including:

  • Bern University, Artorg Center Biomedical Engineering Research (Bern, Switzerland)
  • Texas A&M Engineering Experiment Station (Texas, USA)
  • École Polytechnique Fédérale de Lausanne (EPFL, Switzerland)
  • Swiss Federal Institute of Technology, Zürich (ETH, Switzerland)
  • Vivitro Systems, Inc. (Victoria, Canada)
  • Helmholtz-Institute (Aachem, Germany)
  • California Institute of Technology, CALTECH (Pasadena, California, USA.)
  • Simulog (Toulouse, France)



In-vivo testing

  Animal 0934- KUL Leuven


Outstanding in-vivo results after long-term implantation in the aortic, mitral, and pulmonary positions without any anticoagulant